|  |  | Fetal haplotypes | Maternal haplotypes | Combined | ||||
---|---|---|---|---|---|---|---|---|---|
Markers | Haplotype | freq | RR | 95% CI | p | RR | 95% CI | p | Overall p |
rs6760780-rs3923384-rs6434317 | T-A-C | 0.810 | 1.00 | - | - | 1.00 | - | - | 0.006 |
 | T-A-A | 0.116 | 0.55 | 0.33, 0.92 | 0.021 | 0.97 | 0.59, 1.60 | 0.920 |  |
 | A-A-A | 0.035 | 0.33 | 0.13, 0.85 | 0.020 | 1.50 | 0.64, 3.50 | 0.351 |  |
 | A-G-A1 | 0.034 | 2.11 | 1.05, 4.22 | 0.035 | 0.84 | 0.44, 1.60 | 0.594 |  |
rs3923384-rs6434317-rs6434322 | A-C-G | 0.810 | 1.00 | - | - | 1.00 | - | - | 0.003 |
 | A-A-G1 | 0.154 | 0.49 | 0.31, 0.77 | 0.002 | 1.08 | 0.70, 1.67 | 0.724 |  |
 | G-A-A | 0.034 | 2.09 | 1.03, 4.19 | 0.042 | 0.83 | 0.44, 1.60 | 0.588 |  |
rs6434317-rs6434322-rs10165260 | C-G-A | 0.810 | 1.00 | - | - | 1.00 | - | - | 0.003 |
 | A-G-A1 | 0.154 | 0.49 | 0.31, 0.76 | 0.002 | 1.07 | 0.69, 1.65 | 0.747 |  |
 | A-A-G | 0.034 | 2.09 | 1.03, 4.18 | 0.040 | 0.83 | 0.43, 1.60 | 0.584 |  |
rs6434322-rs10165260-rs7420331 | G-A-A | 0.810 | 1.00 | - | - | 1.00 | - | - | 0.003 |
 | G-A-G | 0.154 | 0.49 | 0.31, 0.77 | 0.001 | 1.08 | 0.70, 1.67 | 0.726 |  |
 | A-G-A | 0.035 | 2.09 | 1.03, 4.19 | 0.041 | 0.83 | 0.44, 1.61 | 0.592 |  |
rs10165260-rs7420331-rs13024858 | A-A-A | 0.762 | 1.00 | - | - | 1.00 | - | - | 0.010 |
 | A-G-A | 0.149 | 0.50 | 0.31, 0.79 | 0.003 | 1.00 | 0.64, 1.58 | 0.993 |  |
 | A-A-C | 0.047 | 1.20 | 0.58, 2.44 | 0.631 | 0.57 | 0.27, 1.20 | 0.138 |  |
 | G-A-A | 0.028 | 1.74 | 0.72, 4,24 | 0.211 | 0.50 | 0.21, 1.19 | 0.122 |  |
 | G-A-C | 0.008 | 2.37 | 0.71, 7.54 | 0.151 | 1.70 | 0.56, 5.11 | 0.343 |  |
rs7420331-rs13024858-rs6752781 | A-A-A | 0.794 | 1.00 | - | - | 1.00 | - | - | 0.016 |
 | C-A-A | 0.151 | 0.48 | 0.30, 0.77 | 0.002 | 1.03 | 0.65, 1.60 | 0.913 |  |
 | A-C-G | 0.053 | 1.43 | 0.77, 2.63 | 0.259 | 0.81 | 0.44, 1.48 | 0.492 |  |