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Table 3 Significant SNPs in COL5A2 (collagen V alpha-2) and COL5A1 (collagen V alpha-1)

From: Candidate gene analysis of spontaneous preterm delivery: New insights from re-analysis of a case-control study using case-parent triads and control-mother dyads

    

Fetal

Maternal

Combined

gene

snp

allele

MAF

RR

95% CI

p

RR

95% CI

p

overall p

COL5A2

rs3923384

G

0.034

2.29

1.12, 4.54

0.021

0.83

0.43, 1.59

0.568

0.048

 

rs6434322

A

0.034

2.29

1.12, 4.54

0.021

0.83

0.43, 1.59

0.568

0.048

 

rs10165260

G

0.034

2.29

1.12, 4.54

0.021

0.83

0.43, 1.59

0.568

0.048

 

rs7420331

G

0.154

0.47

0.30, 0.73

0.001

1.09

0.70, 1.69

0.710

0.003

COL5A1

rs4842161

C

0.482

1.32

0.99, 1.75

0.060

0.75

0.57, 1.00

0.055

0.024

 

rs3124932

A

0.433

1.53

1.14, 2.03

0.005

0.78

0.58, 1.04

0.084

0.003

 

rs12005720

G

0.137

0.83

0.56, 1.22

0.343

1.61

1.08, 2.40

0.018

0.034

 

rs3128621

A

0.440

1.49

1.12, 1.99

0.008

0.70

0.53, 0.93

0.015

0.001

 

rs4842167

G

0.388

1.51

1.13, 2.03

0.007

0.70

0.52, 0.93

0.016

0.001

 

rs3811161

G

0.509

0.70

0.52, 0.93

0.012

1.32

0.99, 1.75

0.060

0.007

 

rs3811152

G

0.092

0.59

0.36, 0.95

0.032

1.72

1.05, 2.79

0.031

0.008

 

rs10745387

A

0.405

1.36

1.02, 1.82

0.037

0.75

0.56, 1.00

0.055

0.016

  1. Case-parent triad analysis
  2. 1 Results are not corrected for multiple testing.
  3. 2 A multiplicative model is assumed.
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BMC Medical Genetics

ISSN: 1471-2350

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