Table 4 Comparison between genotypes of the SNP 163 A/G OPG rs3102735 and 245 T/G OPG rs3134070 in PHPT patients

	163 A/G OPGrs3102735		p	245 T/G OPGrs3134070		p
	AA	61.7 ± 12.4		TT	61.2 ± 12.8
Age	AG	61.0 ± 14.2	0.449	TG	64.3 ± 14.7	0.298
(years)	GG	67.8 ± 15.2		GG	70.5 ± 7.7
	AA	28.8 ± 5.1		TT	28.6 ± 4.9
BMI	AG	28.4 ± 4.7	0.793	TG	29.5 ± 5.1	0.663
(kg/m²)	GG	28.6 ± 3.5		GG	28.6 ± 3.5
	AA	1.02 ± 0.32		TT	1.01 ± 0.30
Creatinine	AG	1.02 ± 0. 22	0.580	TG	1.05 ± 0.23	0.836
(mg/dL)	GG	0.89 ± 0.16		GG	1.03 ± 0.05
	AA	140 (32-873)		TT	134 (32-873)
PTH	AG	144 (50-1279)	0.927	TG	203 (55-1279)	0.314
(pg/mL)	GG	164 (61-747)		GG	252 (132-373)
	AA	0.879 ± 0.142		TT	0.869 ± 0.142
LS BMD	AG	0.863 ± 0.147	0.473	TG	0.919 ± 0.162	0.234
(g/cm²)	GG	0.826 ± 0.267		GG	0.672
	AA	0.680 ± 0.104		TT	0.680 ± 0.102
Fem. Neck	AG	0.685 ± 0.092	0.136	TG	0.710 ± 0.090	0.151
BMD (g/cm²)	GG	0.751 ± 0.139		GG	0.747 ± 0.053
	AA	0.834 ± 0.144		TT	0.833 ± 0.140
Total Hip	AG	0.831 ± 0.128	0.241	TG	0.848 ± 0.134	0.484
BMD (g/cm²)	GG	0.906 ± 0.135		GG	0.881 ± 0.008
	AA	0.629 ± 0.096	<0.05	TT	0.616 ± 0.097	<0.05
1/3 Rad	AG	0.635 ± 0.103	AA-GG: 0,038	TG	0.654 ± 0.100	GG-TT: 0,003
BMD (g/cm²)	GG	0.501 ± 0.147	AG-GG: 0,037	GG	0.326	GG-TG: 0,01

Data shown as mean ± SD or median and range for non normal variables. LS: lumbar spine. Fem. Neck: femoral neck. 1/3 Rad: third distal radius. BMD: bone mineral density. Number of subjects: OPG 163: AA = 205, AG = 86, GG = 6. OPG 245
TT = 266, TG = 30, GG = 2 (except for LS BMD and 1/3 Rad BMD GG data = 1 subject).

ISSN: 1471-2350