Table 2 Rare variants identified in ZNF750
From: Association analysis identifies ZNF750 regulatory variants in psoriasis
Name | Position | Property (PolyPhen2 impact) | Alleles | F_case | F_control | Fisher P |
|---|---|---|---|---|---|---|
Novel_1 (c.-597C>T) | 78391506 | Promoter | C/T | 0 of 1312 | 1 of 745 | 0.363 |
Novel_2 (c.-458G>A) | 78391367 | Promoter | G/A | 1 of 1309 | 0 of 746 | 1.000 |
Novel_3 (c.-261G>A) | 78391170 | Exon 1, 5' UTR | G/A | 1 of 1309 | 0 of 746 | 1.000 |
Novel_4 (c.-233 C>T) | 78391142 | Exon 1, 5' UTR | C/T | 4 of 1306 | 0 of 746 | 0.303 |
Novel_5 (c.-232G>A) | 78391141 | Exon 1, 5' UTR | G/A | 1 of 1311 | 0 of 746 | 1.000 |
Novel_6 (c.-45G>C) | 78383664 | Exon 2, 5' UTR | G/C | 1 of 1349 | 0 of 746 | 1.000 |
Novel_7 (c.-36A>G) | 78383655 | Exon 2, 5' UTR | A/G | 1 of 1349 | 0 of 746 | 1.000 |
Novel_8 (c.-32G>A) | 78383651 | Exon 2, 5' UTR | G/A | 1 of 1349 | 0 of 746 | 1.000 |
Novel_9 | 78383521 | Exon 2, T33T | T/C | 1 of 1349 | 0 of 746 | 1.000 |
Novel_10 | 78383438 | Exon 2, R61Q (possibly) | G/A | 2 of 1348 | 1 of 745 | 1.000 |
Novel_11 | 78383402 | Exon 2, P73L (probably) | C/T | 0 of 1350 | 1 of 745 | 0.357 |
Novel_12 | 78383393 | Exon 2, T76I (benign) | C/T | 0 of 1350 | 1 of 745 | 0.357 |
Novel_13 | 78383325 | Exon 2, D99N (probably) | G/A | 1 of 1349 | 1 of 745 | 1.000 |
Novel_14 | 78383272 | Exon 2, E116E | G/A | 1 of 1349 | 0 of 746 | 1.000 |
Novel_15 | 78383216 | Exon 2, A135E (benign) | C/A | 0 of 1350 | 1 of 745 | 0.357 |
Novel_16 | 78383196 | Exon 2, A142T (possibly) | G/A | 1 of 1349 | 0 of 746 | 1.000 |
Novel_17 | 78382899 | Exon 2, E241Q (probably) | G/C | 1 of 1357 | 0 of 752 | 1.000 |
Novel_18 | 78382882 | Exon 2, F246F | T/C | 0 of 1358 | 1 of 751 | 0.356 |
rs35283702 | 78382791 | Exon 2, G277R (probably) | G/A | 15 of 1343 | 7 of 745 | 0.825 |
Novel_19 | 78382759 | Exon 2, H287Q (possibly) | C/G | 1 of 1357 | 0 of 752 | 1.000 |
Novel_20 | 78382489 | Exon 2, F377L (benign) | C/G | 0 of 1374 | 1 of 763 | 0.359 |
rs34687659 | 78382445 | Exon 2, Q392R (possibly) | A/G | 0 of 1374 | 1 of 763 | 0.359 |
Novel_21 | 78382401 | Exon 2, A407T (probably) | G/A | 1 of 1373 | 0 of 764 | 1.000 |
Novel_22 | 78382375 | Exon 2, P415P | G/A | 2 of 1372 | 2 of 762 | 0.622 |
Novel_23 | 78382326 | Exon 2, D432H (possibly) | G/C | 2 of 1372 | 0 of 764 | 0.540 |
Novel_24 | 78382188 | Exon 2, V478I (benign) | G/A | 0 of 1374 | 1 of 763 | 0.359 |
Novel_25 | 78382160 | Intron 2 | C/A | 1 of 1373 | 0 of 764 | 1.000 |
Novel_26 | 78382155 | Intron 2 | A/C | 1 of 1373 | 0 of 764 | 1.000 |
Novel_27 | 78382047 | Intron 2, 5 bp from exon 3 | T/C | 1 of 1373 | 0 of 764 | 1.000 |
rs35792712 | 78382015 | Exon 3, P488P | T/G | 0 of 1374 | 1 of 763 | 0.359 |
Novel_28 | 78381714 | Exon 3, G589R (benign) | G/C | 1 of 1365 | 0 of 766 | 1.000 |
Novel_29 | 78381508 | Exon 3, A657A | G/A | 1 of 1365 | 0 of 766 | 1.000 |
Novel_30 | 78381034 | Exon 3, 3' UTR | G/A | 1 of 1357 | 0 of 756 | 1.000 |
Novel_31 | 78380851 | Exon 3, 3' UTR | A/G | 1 of 1365 | 2 of 752 | 0.290 |
Novel_32 | 78380743 | Exon 3, 3' UTR | A/G | 2 of 1364 | 0 of 754 | 0.541 |
Novel_33 | 78380697 | Exon 3, 3' UTR | T/G | 1 of 1365 | 0 of 754 | 1.000 |
Novel_34 | 78380590 | 3' Downstream | T/C | 2 of 1318 | 1 of 751 | 1.000 |
Novel_35 | 78380548 | 3' Downstream | G/A | 17 of 1305 | 9 of 743 | 1.000 |