Table 3 Single locus analysis of quantitative metabolic traits and surrogate measures of IR

rs3780378

TT ( n = 186)

TC (n = 358)

CC (n = 179)

Mean ± SD

Mean ± SD

Mean ± SD

p

p^a

p^b

TG (mg/dL)

120.61 ± 67.76

144.04 ± 104.745

150.17 ± 106.38

0.001 ^c

ns

ns

TG/HDL-C

3.27 ± 2.60

3.99 ± 3.84

4.39 ± 4.68

0.004 ^c

ns

ns

LAP

44.42 ± 37.72

54.58 ± 49.32

58.89 ± 50.77

0.003 ^c

ns

ns

TT ( n = 187)

TC + CC (n = 537)

Mean ± SD

Mean ± SD

p

p^a

p^b

TG (mg/dL)

120.61 ± 67.76

146.09 ± 105.23

0.00017 ^c

0.006

0.009

TG/HDL-C

3.27 ± 2.60

4.13 ± 4.13

0.001 ^c

0.008

0.011

LAP

44.42 ± 37.72

56.00 ± 49.80

0.0011 ^c

0.004

0.006