Identification of novel mutations in Chinese Hans with autosomal dominant polycystic kidney disease

BMC Medical Genetics

Table 1 General clinical data of the studied patients

General description	Rate (N = 65)^a
%Female	49.3%
Average age at the time of test (years)	47.2 (range, 28-79)
%ESRD^b	29.8%
Average GFR (mL/min)^c	41.4 (range, 3.4-105.1)
Average Serum creatinine concentration (μmol/L)	310.8 (range, 52.0-1022.8)
Average BUN (mmol/L) ^c	12.3 (range, 3.4-41.8)
%With family history^d	72.6%

^a Data summarized from 65 probands.
^b ESRD defined as transplant, dialysis, or Modification of Diet in Renal Disease (MDRD) GER < 10 mL/min.
^c MDRD GFR = 186 × (Scr/88.4)^-1.154 × Age^-0.203 × (0.742 if female). Scr, Serum Creatinine in μmol/L; BUN, blood urea nitrogen in mmol/L.
^d Data obtained from the probands and their living family members.

ISSN: 1471-2350