Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population

BMC Medical Genetics

Table 1 Polymorphic variants detected within BMP4.1 and BMP4.2 in NSCLP cases and controls

Promoter	Polymorphism	Genetic position	Chromosome position^a	Variation	MAF^b		Odds Ratio (95% C.I.)	p-value
					Cases	Controls
BMP4.1	rs2855527	c.-5729	54424669	T > G	0.0032	0.0030	1.04 (0.09-11.55)	0.972
	rs77671695	c.-5098	54424038	T > G	0.040	0.055	0.72 (0.37-1.38)	0.322
	delAACCCGGG	c.-3066_c.-3059	54422006-54421999	ins > del	0.039	0.059	0.65 (0.33-1.27)	0.202
	rs2855530	c.-2977	54421917	C > G	0.418	0.369	1.23 (0.93-1.62)	0.146
BMP4.2	rs113141288	c.-2932	54421872	G > T	0.041	0.052	0.78 (0.41-1.50)	0.455
	rs76953585	c.-2679	54421619	C > T	0.044	0.054	0.79 (0.42-1.50)	0.484
	rs113562279	c.-2608	54421548	G > T	0.038	0.052	0.70 (0.35-1.37)	0.295

ISSN: 1471-2350