Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India

Table 1 Baseline characteristics of (A) families for the primary sample of Indian multicase VL families, and (B) the Indian case-control cohorts

(A) Family Structure	Number*
N^o families	137
N^o nuclear families	176
Nuclear families with 1 affected sib	63
Nuclear families with 2 affected sibs	95
Nuclear families with 3 affected sibs	14
Nuclear families with 4 affected sibs	2
Nuclear families with 5 affected sibs	2
N^o affected offspring	313
N^o affected parents	63
Total N^o affected individuals	394
Total N^o individuals	836
(B) Case-Control Sample	Number
Cases (no.)	958
Male	571
Female	387
Mean age at study encounter ± SD (yr)	31.2 ± 16.7
Range	3-73
Mean age at onset of VL ± SD (yr)	26.8 ± 15.3
Religious Group (no.)
Hindu	850
Muslim	108
Controls (no.)	1015
Male	570
Female	445
Mean age at study encounter ± SD (yr)	31.8 ± 15.9
Religious Group (no.)
Hindu	885
Muslim	130

ISSN: 1471-2350