Skip to main content

Table 1 Baseline Characteristics. Clinical characteristics of study subjects by Race and Albuminuric Status

From: Genetic variation of Glucose Transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) Study

 

Stage 1

Stage 2

 

European Americans (n = 1803)

European Americans (n = 6319)

Characteristic

Control Subjects

Albuminuria Cases

Control Subjects

Albuminuria Cases

   N

1646

157

5945

374

Age, mean(SD), y

63.2

(5.6)

64.9

(5.6)***

62.8

(5.6)

65.2

(5.6)***

Male, No. (%)

802

(48.7)

92

(58.6)*

2655

(44.7)

199

(53.2)**

Hypertension, No. (%)

731

(44.4)

111

(70.7)***

2266

(38.1)

269

(71.9)***

Type 2 Diabetes, No. (%)

480

(29.2)

84

(53.5)***

428

(7.2)

103

(27.5)***

Body mass index, kg/m 2

29.0

(5.5)

30.0

(6.3)*

28.0

(5.0)

28.8

(6.0)**

SBP (mmHg)

126.8

(17.4)

135.7

(20.4)***

124.4

(17.8)

138.3

(23.2)***

DBP (mmgHg)

69.7

(10.0)

70.0

(11.1)

69.5

(9.6)

72.5

(12.1)***

Fasting Glucose (mg/dL) §

115.4

(34.9)

134.4

(52.2)***

102.1

(21.2)

116.8

(43.4)***

GFR, ml/min per 1.73 m2

81.7

(16.9)

75.0

(25.7)***

80.7

(16.1)

76.1

(22.3)***

ACR, μg/mg, median (25%ile, 75%ile)

3.7

(1.8,6.7)

102.6

(47.4,275.0)***

3.6

(2.0,6.5)

74.8

(44.4,166.7)***

 

African Americans (n = 1135)

African Americans (n = 1021)

Characteristic

Control Subjects

Albuminuria Cases

Control Subjects

Albuminuria Cases

N

987

148

875

146

Age, mean(SD), y

61.3

(5.5)

63.0

(5.8)†††

61.8

(5.7)

62.5

(5.7)

Male, No. (%)

336

(34.0)

44

(29.7)

324

(37.0)

54

(37.0)

Hypertension, No. (%)

615

(62.3)

127

(85.8)†††

558

(63.8)

127

(87.0) †††

Type 2 Diabetes, No. (%)

217

(22.0)

80

(54.1)†††

196

(22.4)

80

(54.8) †††

Body mass index, kg/m 2

30.7

(6.5)

30.8

(6.6)

30.3

(5.9)

31.4

(6.6) †

SBP (mmHg)

131.2

(18.4)

144.4

(23.2)†††

132.0

(18.9)

144.8

(22.5) †††

DBP (mmgHg)

75.0

(10.0)

78.2

(13.0)†††

75.7

(10.1)

78.5

(11.9) ††

Fasting Glucose (mg/dL) §

114.3

(39.6)

136.4

(62.2)†††

112.7

(38.5)

137.9

(62.8) †††

GFR, ml/min per 1.73 m2

91.5

(19.0)

83.0

(29.8) †††

90.9

(21.0)

80.7

(29.3) †††

ACR, μg/mg, median (25%ile, 75%ile)

1.9

(0.7,4.7)

95.9

(47.2,363.2)†††

2.2

(0.8,5.2)

81.7

(44.7,249.7) †††

  1. Data are means (SD), number (%), or for ACR median (25%ile, 75%ile). European Americans: * P < 0.05; **P < 0.01; ***P < 0.001.
  2. African Americans: †P < 0.05; ††P < 0.01; †††P < 0.001.
  3. §Individuals with fasting glucose measured. Evaluation set (European Americans n = 1582 controls and n = 150 cases; African Americans n = 922 controls and n = 113 cases). Valdiation set (European Americans n = 5822 controls and n = 356 cases; African Americans n = 787 controls and n = 113 cases).
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us