Skip to main content

Table 5 Meta-analysis of effects of rs9514089 on serum cholesterol and triglyceride levels in the Sorbs, Aachen cohort and Stuttgart cohort

From: Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts

 

Sorbs

 

Aachen

 

Stuttgart

   

Trait

p (ADD)

beta (ADD)

p (ADD)

beta (ADD)

p (ADD)

beta (ADD)

p meta

beta meta

  

[95% CI]

 

[95% CI]

 

[95% CI]

 

[95% CI]

total cholesterol [mmol/l]

0.17

0.01

0.28

-0.024

0.06

-0.048

0.91

0.001

  

[-0.005; 0.028]

 

[-0.067; 0.019]

 

[-0.097; 0.001]

 

[-0.014; 0.016]

triglycerides [mmol/l]

0.41

0.018

0.92

-0.004

0.37

-0.062

0.69

0.007

  

[-0.025; 0.061]

 

[-0.078; 0.070]

 

[-0.197; 0.073]

 

[-0.029; 0.043]

  1. Meta-analysis of three independent cohorts (Sorbs N = 907, Aachen N = 358, Stuttgart N = 122). Analyses were performed under the additive mode of inheritance in a fixed effects model. Only subjects without any lipid-lowering medication were included in the analyses. Results were assessed in a linear regression model adjusted for age, sex and BMI and effect directions are standardized to the minor allele.
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us