Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk

Table 2 Regression coefficients used in models generating Framingham risk scores for 10-year risk of general cardiovascular disease

The 10-year risk for women can be calculated as 1-0.95012^{exp(ΣβX - 26.1931)} where Beta is the regression coefficient and × is the level for each risk factor; the risk for men is given as 1-0.88936^{exp(ΣβX - 23.9802)} [20]

ISSN: 1471-2350