Table 2 Clinical characteristics of controls and patients
From: A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia
Characteristics | Controls (N = 305) | Patients (N = 155) | p-valuea | cOR (95% CI) | p-valueb |
|---|---|---|---|---|---|
Age | 29 ± 7 (23-36) | 30 ± 7 (23-37) | 0.103 | 1.04 (0.99-1.09) | 0.099 |
BMI | 22.46 ± 2.60 (16.32-28.50) | 22.80 ± 2.45 (17.74-29.40) | 0.063 | 1.12 (1.02-1.22) | 0.021 |
Smoking | 13 (4.26) | 3 (1.94) | 0.309 | 0.44 (0.12-1.58) | 0.210 |
Gravidity: | 0.076 | ||||
1 | 259 (84.92) | 121 (78.06) | 1 | ||
2 | 35 (11.48) | 21 (13.55) | 1.28 (0.72-2.30) | 0.400 | |
3 | 11 (3.61) | 13 (8.39) | 2.53 (1.10-5.81) | 0.029 | |
Ethnicity: | 0.690 | ||||
Caucasian | 291 (95.41) | 145 (93.55) | 1 | ||
African | 8 (2.62) | 6 (3.87) | 1.51 (0.51-4.42) | 0.457 | |
Asian | 6 (1.97) | 4 (2.58) | 1.34 (0.37-4.82) | 0.656 | |
Diabetes Mellitus | 4 (1.31) | 7 (4.52) | 0.071 | 3.56 (1.03-12.4) | 0.046 |
Pre-existing arterial hypertension | 8 (2.62) | 12 (7.74) | 0.021 | 3.12 (1.25-7.79) | 0.015 |
Maternal PE antecedent | 10 (3.28) | 13 (8.39) | 0.032 | 2.70 (1.16-6.31) | 0.022 |