Table 1 Demographic characteristics of COPD patients, smokers and healthy individuals included in the association study
Variable | Cases (n = 202) | Smoking controls (n = 90) | Healthy controls (n = 432) | P-value |
|---|---|---|---|---|
Gender (male %) | 76 | 49 | 75 | < 0.0001 |
Age (years)* | 62 ± 10 | 48 ± 9 | 53 ± 8 | < 0.0001 |
Smoking history(pack-yrs) † * | 63 ± 27 | 35 ± 18 | __ | < 0.0001 |
FEV 1 * | 1.53 ± 0.7 | 3.06 ± 0.71 | __ | < 0.0001 |
FEV 1 % pred* | 56 ± 22 | 102 ± 15 | __ | < 0.0001 |
FVC % pred* | 86 ± 23 | 108 ± 16 | __ | < 0.0001 |
FEV 1 /FVC* | 52 ± 12 | 79 ± 6 | __ | < 0.0001 |
6MWD (m) * | 490 ± 86 | __ | __ | |
BMI (Kg/m 2 )* | 27 ± 5 | __ | __ | |
BODE index* | 2 ± 0.7 | __ | __ | |
BODE index < 2 ‡ | 111 | __ | __ | |
BODE index ≥ 3 ‡ | 52 | __ | __ | |
GOLD I-II ‡ | 119 | __ | __ | |
GOLD III-IV ‡ | 83 | __ | __ |