Skip to main content

Table 3 Characteristics of patients by MTHFD1L genotype (N = 3095).

From: Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome

Outcome   GG
(n = 1366)
AG
(n = 1327)
AA
(n = 402)
PValue
   Patient Died 395 (12.8%) 137 (10.0%) 182 (13.7%) 76 (18.9%) < 0.001
   Time (Year)      0.120
Mean ± SD 2.8 ± 1.2 2.8 ± 1.1 2.7 ± 1.2 2.8 ± 1.4  
Median (IQR*) 2.7 (2.0, 3.6) 2.8 (2.1, 3.7) 2.6 (2.0, 3.6) 2.8 (1.8, 3.6)  
Demographics and History      
   Age 59.3 ± 12.5 59.9 ± 12.2 59.1 ± 12.8 57.9 ± 12.4 0.010
   Sex      0.003
Male 2095 (67.7%) 944 (69.1%) 909 (68.5%) 242 (60.2%)  
Female 1000 (32.3%) 422 (30.9%) 418 (31.5%) 160 (39.8%)  
   Race Category      < 0.001
White/Caucasian 2315 (74.9%) 1189 (87.3%) 943 (71.1%) 183 (45.6%)  
Black/African American 607 (19.7%) 109 (8.0%) 303 (22.9%) 195 (48.6%)  
Other 167 (5.4%) 64 (4.7%) 80 (6.0%) 23 (5.7%)  
Unknown 6 4 1 1  
  1. *IQR: interquartile range