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Table 3 Number of patients who had HLA-B*5801 allele positive and summary odds ratios

From: Association of HLA-B*5801 allele and allopurinol-induced stevens johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis

Author Year HLA-B*5801
Positive/Total
Odds Ratio (OR) 95% Confidence Interval
   SJS/TEN Cases
(n)
Controls
(n)
  
Matched-control      
Hung SI [10] 2005 21/21 20/135 242.27 14.11-4158.76
Tassaneeyakul W [13] 2009 27/27 7/54 348.33 19.15-6336.86
Kang HR [14] 2011 4/5 6/57 34.00 3.25-356.12
Jung JW [15] 2011 2/2 41/432 47.17 2.23-999.15
Pooled OR     96.60 24.49-381.00
Population-control      
Hung SI [10] 2005 21/21 19/93 164.28 9.52-2833.92
Kaniwa N [11] 2008 4/10 6/493 54.11 12.08-242.41
Lonjou C [12] 2008 19/31 28/1822 101.45 44.98-228.82
Kang HR [14] 2011 4/5 59/485 28.88 3.17-262.79
Jung JW [15] 2011 2/2 59/485 35.84 1.70-755.61
Pooled OR     79.28 41.53-151.35
  1. Abbreviations: SJS = Stevens-Johnson Syndrome, TEN = Toxic Epidermal Necrolysis; OR = Odds Ratio