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Table 2 Patients' demographic information

From: Association of HLA-B*5801 allele and allopurinol-induced stevens johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis

Author Year % Male Mean age,
yr (range)
Ethnicity Country Allopurinol Dose, mg/day (range) Actual Duration of Allopurinol Exposure
   SJS/TEN Cases Controls SJS/TEN Cases Controls    Cases Control Cases Control
Hung SI [10] 2005 52.4 92.6a 62.4 (25-91) 56.0 (21-84)b Han Chinese Taiwan 100
(50-300)
150
(100-400)
26 d
(~1-56 d)
22 m
(6-107 m)
Kaniwa N [11] 2008 80.0 NA 70.9 (53-83) NA Japanese Japan NR NR NR NR
Lonjou C [12] 2008 58.1 NA 55.0 (21-83) NA Mixed European Populationc NR NR NR NR NR
Tassaneeyakul W [13] 2009 55.6 79.63 65.0 (38-81) 63.5 (46-90) Thai Thailand NR NR 14 d
(3-50 d)
26 m
(3-600 m)
Kang HR [14] 2011 60.0 64.9d 50.0 (42-80) 51.0 (20-76)d Korean Korea 200
(100-300)
100
(50-200)
0.7 m
(0.2-1.1 m)
29.1 m
(6-72 m)
Jung JW [15] 2011 43.8 73.6d 41.4 (27-56) 35.9 (18-54)d Korean Korea 112.5
(74-151)
100
(50-150)
59 d
(14-105 d)
887 d
(66-1708 d)
  1. Abbreviations: SJS = Stevens-Johnson Syndrome, TEN = Toxic Epidermal Necrolysis; NR = No Report; NA = Not Applicable; d = day(s); m = month(s)
  2. a The percent male of matched-controls (% male in population controls is 55.91).
  3. b Mean age in matched-controls (mean age in population controls is 53.9 (22-91)).
  4. c Including Asian, South American, African, and European.
  5. d The values from matched-controls group.