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Table 1 Characteristics of participants in the rate of lung function decline sub-study and the baseline lung function sub-study

From: Effect of heme oxygenase-1 polymorphisms on lung function and gene expression

 

Rate of decline study

Baseline study

 

Fast decline (n = 278)

Non decline (n = 304)

P value

Low function (n = 535)

High function (n = 533)

P value

Female/Male

115/163

101/203

0.04

205/330

180/353

0.12

Age (years)

49.5 ± 6.7

47.6 ± 7.0

0.0005

50.7 ± 6.9

46.2 ± 6.9

< 0.0001

Smoking (pack-years)

43.0 ± 18.3

38.3 ± 17.4

0.003

45.3 ± 18.5

35.4 ± 18.5

< 0.0001

ΔFEV1, % predicted/yr*

-3.44 ± 1.17

0.68 ± 1.05

< 0.0001

-0.78 ± 1.85

-0.75 ± 1.39

0.73

Baseline FEV1, % predicted†

74.8 ± 8.3

80.0 ± 8.7

< 0.0001

62.6 ± 2.3

91.8 ± 2.3

< 0.0001

  1. Data are presented as means ± SD. Lung function was measured after administration of bronchodilator.
  2. * Change in lung function per year over a 5 year period
  3. † Lung function at the start of the Lung Health Study