Figure 1
From: Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever
Expression Level of MEFV in FMF patients and Healthy Controls. Expression levels were measured by quantitative real time PCR analysis. RNA was obtained from peripheral leukocytes as described in materials and methods. B2M gene was used as reference gene and ΔCT method were used to relative quantification. MEFV mRNA level was analyzed in 51 FMF patients and 11 healthy controls. The bars represent standard deviations. Two tail Student's t-test was used to compare the MEFV expression levels. The expression was significantly lower in FMF patients compared to healthy controls (P = 0.031).