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Table 3 SNPs with differential association (p < 0.001) with LVM among High and Low Waist Circumference (WC)"

From: A follow-up study for left ventricular mass on chromosome 12p11 identifies potential candidate genes

      Overall (N = 897) High WC (N = 495) Low WC (N = 402)   
SNP MB Gene Function Minor Allele Beta SE P* Beta SE P* Beta SE P* Difference in Betas P†
rs1157480 30.264 TMTC1 flanking A 0.004 0.014 7.88E-01 0.053 0.019 6.30E-03 -0.056 0.021 8.20E-03 0.109 1.37E-04
rs1124636 26.424 ITPR2 intron T -0.016 0.014 2.54E-01 0.032 0.019 9.31E-02 -0.072 0.020 2.85E-04 0.104 1.45E-04
rs9669515 30.261 TMTC1 flanking T 0.002 0.014 8.74E-01 0.049 0.019 1.04E-02 -0.055 0.021 8.68E-03 0.104 2.31E-04
rs7970841 30.274 TMTC1 flanking T -0.007 0.015 6.31E-01 0.042 0.020 3.04E-02 -0.064 0.021 3.03E-03 0.106 2.46E-04
rs7963790 38.515 SLC2A13 intron C 0.022 0.013 1.03E-01 0.064 0.017 2.40E-04 -0.030 0.019 1.20E-01 0.095 2.87E-04
rs10877703 38.561 SLC2A13 intron A 0.012 0.013 3.37E-01 0.052 0.017 2.47E-03 -0.041 0.019 3.22E-02 0.093 2.87E-04
rs1679695 28.845 CCDC91 flanking T -0.044 0.022 5.20E-02 -0.106 0.028 2.12E-04 0.050 0.035 1.55E-01 0.156 5.56E-04
rs326644 32.293 BICD1 intron C -0.009 0.012 4.41E-01 0.024 0.016 1.34E-01 -0.059 0.018 1.23E-03 0.083 5.73E-04
rs261889 32.371 BICD1 intron T 0.014 0.014 3.40E-01 -0.030 0.019 1.11E-01 0.066 0.021 1.65E-03 0.096 6.18E-04
rs326641 32.291 BICD1 intron T 0.015 0.014 2.75E-01 0.059 0.018 1.23E-03 -0.032 0.020 1.06E-01 0.091 6.82E-04
rs2650128 32.352 BICD1 intron G 0.014 0.015 3.32E-01 -0.026 0.019 1.77E-01 0.074 0.023 1.10E-03 0.100 7.10E-04
rs4356315 31.105 DDX11 flanking G 0.014 0.012 2.38E-01 0.050 0.015 1.18E-03 -0.028 0.017 1.07E-01 0.078 7.21E-04
rs11610493 40.345 PDZRN4 flanking G 0.014 0.013 2.57E-01 -0.023 0.017 1.70E-01 0.061 0.018 1.05E-03 0.084 7.82E-04
  1. *adjusted for PCA1, PCA2, age, sex, hypertension, diabetes, BMI, WC, and years between LVM and risk factor measurements
  2. † p-value calculated using a normal approximation to test for differences between the beta coefficients of high and low WC.