Figure 1
From: Association of obesity risk SNPs in PCSK1with insulin sensitivity and proinsulin conversion
Plasma proinsulin (A), glucose (B), and insulin (C) concentrations as well as proinsulin-to-insulin ratio (D) during OGTT in carriers of the PCSK1 SNP rs6235. Data are given as means +/- SEM. P-values for AUC adjusted for gender, age, BMI, and insulin sensitivity are given. Black boxes: homozygous carriers of the minor allele; white circles: heterozygous carriers; black circles: homozygous carriers of the major allele.