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Table 2 Genotype frequencies of GRP78 among cases and controls, and risk of HBV

From: Lack of association between the GRP78 polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population

Loci

Genotypes

Cases (%)

Controls (%)

OR (95% CI)

P

rs391957

GG

275 (54.95)

320 (59.22)

1

 
 

AG

198 (40.00)

200 (37.24)

1.22 (0.94-1.59)

0.137

 

AA

23 (5.05)

19 (3.54)

1.60 (0.84-3.07)

0.354

p-trenda

   

0.106

 

rs17840762

CC

334 (67.39)

366 (67.97)

1

 
 

CT

144 (29.19)

151 (27.93)

1.05 (0.79-1.39)

0.659

 

TT

18 (3.42)

22 (4.10)

0.78 (0.41-1.51)

0.271

p-trenda

   

0.501

 

rs17840761

TT

130 (25.76)

156 (28.86)

1

 
 

CT

236 (47.74)

249 (46.37)

1.17 (0.87-1.59)

0.405

 

CC

130 (26.48)

134 (24.77)

1.24 (0.88-1.75)

0.222

p-trenda

   

0.245

 

rs11355458

d d

275 (54.95)

320 (59.22)

1

 
 

d G

198 (40.00)

200 (37.24)

1.22 (0.94-1.59)

0.137

 

GG

23 (5.05)

19 (3.54)

1.60 (0.84-3.07)

0.354

p-trenda

   

0.106

 

rs16927997

TT

440 (88.83)

480 (89.01)

1

 
 

CT

52 (10.45)

55 (10.24)

1.01 (0.67-1.53)

0.812

 

CC

4 (0.72)

4 (0.74)

1.04 (0.23-4.68)

0.460

p-trenda

   

0.393

 

rs1140763

TT

129 (25.40)

168 (31.10)

1

 
 

CT

236 (48.29)

246 (45.62)

1.36 (0.92-1.79)

0.348

 

CC

131 (26.31)

125 (23.28)

1.51 (0.95-2.06)

0.177

p-trenda

   

0.204

 

rs12009

TT

166 (31.61)

204 (37.80)

1

 
 

CT

222 (45.59)

237 (43.95)

1.25 (0.88-1.61)

0.291

 

CC

108 (21.80)

98 (18.25)

1.53 (0.96-2.08)

0.097

p-trenda

   

0.082

 
  1. Note: OR, odds ratio; d, delete base.
  2. aTest for trend of odds was two sided and was based on likelihood ratio tests assuming a multiplicative model for all cases.