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Table 4 Odds ratios and 95% confidence intervals (OR (CI)) for associations between IL-10 gene polymorphisms and ulcerative colitis (UC) or Crohns disease (CD) in selected case-control studies3.

From: The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

Ncases/control

Trs3024505C1

Grs3024493T1

C-819T2

(rs1800871)

C-592A2

(rs1800872)

G-1082A2

(rs1800896)

Crs2222202T

 

UC

       

1855/3091

1.46 (1.31-1.62)

 

Neg

Neg

neg

 

[29]

203/391

  

neg

 

1.66 (1.30-2.14)

 

[36]

CD

       

1848/1804

1.17 (1.01-1.34)

     

[29]

270/336

 

neg

0.77 (0.58-1.00)

  

1.29 (1.01-1.64)

[30]

234-6/188-231

   

neg

neg

 

[35]

  1. 1rs3024505 and rs3024493 are in complete linkage disequilibrium [30]
  2. 2 IL-10 G-1082A, C-819T, and C-592A are in linkage disequilibrium [32] C-819T, and C-592A are in complete linkage disequilibrium [34]
  3. 3Negative associations are indicated by "Neg"