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Table 6 CAPN10 Haplotype Combinations

From: Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

Diplotype1

Patients

Controls

P

Pc 2

OR3(95% CI)

111/111

132 (0.144) 4

88 (0.118)

0.133

0.864

1.26 (0.94 - 1.70)

111/112

45 (0.049)

23 (0.031)

0.079

0.684

1.63 (0.97 - 2.67)

111/121

260 (0.284)

193 (0.258)

0.268

0.987

1.14 (0.91 - 1.41)

111/221

76 (0.083)

57 (0.076)

0.683

1.000

1.10 (0.76 - 1.56)

112/112

4 (0.004)

3 (0.004)

0.947

1.000

0.81 (0.22 - 3.02)

112/121

115 (0.125)

87 (0.116)

0.624

1.000

1.09 (0.81 - 1.46)

112/221

28 (0.031)

32 (0.043)

0.230

0.974

0.70 (0.42 - 1.18)

121/121

132 (0.144)

131 (0.175)

0.095

0.753

0.79 (0.61 - 1.03)

121/221

35 (0.038)

39 (0.052)

0.194

0.951

0.72 (0.45 - 1.15)

221/221

3 (0.003)

5 (0.007)

0.519

1.000

0.49 (0.13 - 1.98)

112/122

10 (0.011)

7 (0.009)

0.946

1.000

1.17 (0.45 - 2.93)

121/122

58 (0.063)

62 (0.083)

0.148

0.894

0.75 (0.52 - 1.08)

122/122

3 (0.003)

8 (0.011)

0.120

0.833

0.30 (0.10 - 1.16)

122/221

16 (0.017)

13 (0.017)

0.859

1.000

1.00 (0.48 - 2.06)

  1. 1. CAPN10 haplotypes were coded as per the allele (wild-type = 1, mutant = 2) at each locus; the first refers to UCSNP-43, the second to UCSNP-19, and the third to UCSNP-63.
  2. 2. Pc = corrected P, calculated as per the Bonferroni method [Pc = 1 - (1 - P)n)], where n = number of comparisons.
  3. 3. Calculated according to Woolf's method, for specific patient vs. control diplotype carriers.
  4. 4. Number (frequency).