Skip to main content

Table 6 CAPN10 Haplotype Combinations

From: Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

Diplotype1 Patients Controls P Pc 2 OR3(95% CI)
111/111 132 (0.144) 4 88 (0.118) 0.133 0.864 1.26 (0.94 - 1.70)
111/112 45 (0.049) 23 (0.031) 0.079 0.684 1.63 (0.97 - 2.67)
111/121 260 (0.284) 193 (0.258) 0.268 0.987 1.14 (0.91 - 1.41)
111/221 76 (0.083) 57 (0.076) 0.683 1.000 1.10 (0.76 - 1.56)
112/112 4 (0.004) 3 (0.004) 0.947 1.000 0.81 (0.22 - 3.02)
112/121 115 (0.125) 87 (0.116) 0.624 1.000 1.09 (0.81 - 1.46)
112/221 28 (0.031) 32 (0.043) 0.230 0.974 0.70 (0.42 - 1.18)
121/121 132 (0.144) 131 (0.175) 0.095 0.753 0.79 (0.61 - 1.03)
121/221 35 (0.038) 39 (0.052) 0.194 0.951 0.72 (0.45 - 1.15)
221/221 3 (0.003) 5 (0.007) 0.519 1.000 0.49 (0.13 - 1.98)
112/122 10 (0.011) 7 (0.009) 0.946 1.000 1.17 (0.45 - 2.93)
121/122 58 (0.063) 62 (0.083) 0.148 0.894 0.75 (0.52 - 1.08)
122/122 3 (0.003) 8 (0.011) 0.120 0.833 0.30 (0.10 - 1.16)
122/221 16 (0.017) 13 (0.017) 0.859 1.000 1.00 (0.48 - 2.06)
  1. 1. CAPN10 haplotypes were coded as per the allele (wild-type = 1, mutant = 2) at each locus; the first refers to UCSNP-43, the second to UCSNP-19, and the third to UCSNP-63.
  2. 2. Pc = corrected P, calculated as per the Bonferroni method [Pc = 1 - (1 - P)n)], where n = number of comparisons.
  3. 3. Calculated according to Woolf's method, for specific patient vs. control diplotype carriers.
  4. 4. Number (frequency).