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Table 3 Regression Analysis on T2D Risk Associated with CAPN10 Polymorphisms 1

From: Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

   Univariate Multivariate
SNP Genotype P OR (95% CI) P aOR 2(95% CI)
UCSNP-43 G/G 0.647 1.00 (Reference) 3 0.809 1.00 (Reference) 3
  G/A 0.573 1.52 (0.35 - 6.53) 0.827 1.20 (0.24 - 6.12)
  A/A 0.492 1.66 (0.39 - 7.03) 0.708 1.36 (0.27 - 6.85)
UCSNP-19 3R/3R 0.003 1.00 (Reference) 3 0.084 1.00 (Reference) 3
  3R/2R 0.008 1.35 (1.08 - 1.68) 0.923 1.02 (0.66 - 1.58)
  2R/2R 0.002 1.61 (1.20 - 2.18) 0.044 1.40 (1.01 - 1.93)
UCSNP-63 C/C 0.714 1.00 (Reference) 3 0.704 1.00 (Reference) 3
  C/T 0.463 1.29 (0.66 - 2.52) 0.722 1.19 (0.45 - 3.17)
  T/T 0.417 1.31 (0.68 - 2.54) 0.920 1.05 (0.39 - 2.85)
  1. 1. Study subjects comprised 917 cases and 748 age-, gender-, and origin-matched controls subjects.
  2. 2. aOR = adjusted OR; covariates included age, gender, BMI, hypertension, and lipid profile.
  3. 3. Reference group being minor allele non-carriers.