Genetic Variant | Non-Hispanic White | Non-Hispanic Black | Mexican American | SNP X Race/ethnicity | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | β (95% CI) | FDR-adjusted P value* | β (95% CI) | FDR-adjusted P value | β (95% CI) | FDR-adjusted P value | FDR-adjusted P value | ||||||
Crude Analysis | Â | Â | Â | Â | Â | Â | Â | ||||||
High-density lipoprotein cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs854560 (PON1) | -2.23 (-5.15,0.69) | 0.3589 | -0.58 (-2.81,1.65) | 0.869 | 3.59 (1.55,5.64) | 0.0308 | 0.2552 | ||||||
Low-density lipoprotein cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs7412 (APOE) | -16.68 (-27.85,-5.50) | 0.1144 | -20.58 (-29.12,-12.04) | <.0001 | -19.80 (-33.33,-6.28) | 0.066 | 0.8931 | ||||||
Total serum cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs7412 (APOE) | -13.90 (-25.39,-2.41) | 0.1569 | -16.26 (-25.75,-6.77) | 0.0374 | -10.26 (-19.18,-1.33) | 0.2871 | 0.9227 | ||||||
Triglycerides | Â | Â | Â | Â | Â | Â | Â | ||||||
rs5918 (ITGB3) | 0.05 (-0.06,0.17) | 0.7294 | 0.14 (0.07,0.20) | 0.0066 | -0.05 (-0.17,0.06) | 0.613 | 0.4653 | ||||||
Adjusted Analysis** | Â | Â | Â | Â | Â | Â | Â | ||||||
High-density lipoprotein cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs854560 (PON1) | -1.53 (-4.11,1.06) | 0.5062 | -0.09 (-2.20,2.02) | 0.9733 | 3.21 (1.45,4.97) | 0.022 | 0.1535 | ||||||
Low-density lipoprotein cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs7412 (APOE) | -16.87 (-27.94,-5.81) | 0.0968 | -22.52 (-30.01,-15.04) | <.0001 | -21.47 (-31.32,-11.62) | 0.0022 | 0.9012 | ||||||
rs429358 (APOE) | 8.26 (1.19,15.33) | 0.264 | 3.85 (-2.14,9.84) | 0.6169 | 10.54 (6.41,14.67) | <.0001 | 0.9012 | ||||||
rs1799983 (NOS3) | 3.05 (-2.41,8.52) | 0.5284 | 5.28 (-0.42,10.98) | 0.4103 | -4.56 (-7.63,-1.48) | 0.0396 | 0.9012 | ||||||
Total serum cholesterol | Â | Â | Â | Â | Â | Â | Â | ||||||
rs7412 (APOE) | -15.26 (-26.16,-4.36) | 0.0902 | -20.68 (-28.90,-12.47) | <.0001 | -12.54 (-19.89,-5.20) | 0.0198 | 0.9724 | ||||||
rs429358 (APOE) | 9.82 (2.96,16.69) | 0.0902 | 4.35 (-2.30,11.01) | 0.6839 | 11.18 (7.11,15.25) | <.0001 | 0.9724 | ||||||
Triglycerides | Â | Â | Â | Â | Â | Â | Â | ||||||
rs5918 (ITGB3) | 0.02 (-0.07,0.11) | 0.8985 | 0.14 (0.09,0.19) | <.0001 | -0.01 (-0.14,0.11) | 0.8962 | 0.4419 |