Table 2 Single-locus SNP effects for HDL-C with genome control (GC) adjusted P < 7.2 × 10^-8.

rs17482753

8

19832646

8 kb downstream LPL ^a

Triglyceride [7]

0.10

1.27E-08

3.50E-09

-0.191 ± 0.031

rs10503669

8

19847690

23 kb downstream LPL ^a

HDL-C [4, 11]

0.09

3.75E-08

1.14E-08

-0.189 ± 0.031

rs17410962

8

19848080

23 kb downstream LPL ^a

0.12

2.75E-08

4.27E-09

0.173 ± 0.028

rs17489268

8

19852045

27 kb downstream LPL ^a

0.27

2.28E-10

5.97E-11

0.141 ± 0.02

rs17411031

8

19852310

28 kb downstream LPL ^a

HDL-C [7]

0.27

3.06E-10

7.21E-11

-0.14 ± 0.02

rs17489282

8

19852518

28 kb downstream LPL ^a

0.25

2.33E-09

6.54E-10

0.14 ± 0.021

rs4922117

8

19852586

28 kb downstream LPL ^a

0.25

2.28E-09

7.73E-10

-0.124 ± 0.019

rs17411126

8

19855272

31 kb downstream LPL ^a

0.27

6.14E-10

1.23E-10

0.138 ± 0.02

rs765547

8

19866274

42 kb downstream LPL ^a

0.27

1.60E-10

3.07E-11

-0.142 ± 0.02

rs11986942

8

19867445

43 kb downstream LPL ^a

0.33

2.22E-07

5.53E-08

0.112 ± 0.02

rs1837842

8

19868290

44 kb downstream LPL ^a

0.27

2.14E-10

4.09E-11

0.142 ± 0.02

rs1919484

8

19869676

45 kb downstream LPL ^a

0.27

4.12E-10

7.21E-11

-0.143 ± 0.021

rs17259942

12

77072077

OSBPL8-ZDHHC17

0.12

8.61E-08

1.81E-08

0.168 ± 0.028

rs9989419

16

56985139

HERPUD1-CETP ^a

HDL-C [4, 7]

0.40

4.57E-13

5.96E-14

-0.147 ± 0.019

rs1800775

16

56995236

0.5 kb upstream CETP ^a

HDL-C [3, 12]

0.45

1.54E-29

1.64E-30

0.242 ± 0.02

rs7240405

18

47159090

LIPG ^a-ACAA2 ^b

0.16

8.01E-08

1.58E-08

-0.145 ± 0.024

rs4939883

18

47167214

LIPG ^a-ACAA2 ^b

HDL-C [1, 2]

0.17

1.07E-07

1.85E-08

0.142 ± 0.024

rs1943981

18

47169815

LIPG ^a-ACAA2 ^b

0.17

1.49E-07

2.50E-08

0.142 ± 0.024

rs2156552

18

47181668

LIPG ^a-ACAA2 ^b

HDL-C [3, 4]

0.16

5.87E-08

1.14E-08

-0.146 ± 0.024

rs6507945

18

47243912

LIPG ^a-ACAA2 ^b

0.43

4.34E-08

6.91E-09

0.113 ± 0.018