EEG alpha phenotypes: linkage analyses and relation to alcohol dependence in an American Indian community study

BMC Medical Genetics

Table 2 Genetic Loci for EEG traits in an American Indian community

CHR	Trait	LOC (cM)	LOD	Nearest Marker	Nominal p-value	Supporting References (phenotype)
1	Fronto-central alpha	12	4.25	D1S214/ D1S450	0.00012	Gizer et al., unpublished work (Alcohol Dep)
2	Centro-parietal-occipital alpha	92	2.66	D2S286	0.00314	[15] (ASPD); [85] (Alcohol Dep); [94, 95] (Smoking)
4	Fronto-central alpha	98	2.25	D4S2460	0.00318	[13] (Drinking/Dep symptoms); [85] (Alcohol Dep); [86] (Quant Alcohol Phenotype); [87] (Max Drinks); [88, 89] (Drinking)
6	Fronto-central alpha	50	3.90	D6S1575	0.00022	[13] (Alcohol Withdrawal); [90, 92, 93] (Smoking);
11	Fronto-central alpha	30	2.98	D11S4115	0.00118	[15] (ASPD); [96] (Opioid Dep); [97] (Alcohol Dep)
14	Fronto-central alpha	113	2.13	D14S65	0.0039	[51, 98] (Cannabis Dep); [99] (Opioid Dep); [100] (Ever Smoked)
16	Fronto-central alpha	69	2.07	D16S415/ D16S3140	0.0051	[101] (Ever quit smoking)
22	Fronto-central alpha	29	2.38	D22S280/ D22S277	0.00174	[27] (Theta EEG); [75] (LR to alcohol); [[88, 103], Gizer et al., unpublished work (Alcohol Dep); [102] (Smoking)

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