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Table 3 Association of rs975278 with emphysema in smokers

From: Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases

Variables

Subjects with emphysema

(n = 127)

Subjects without emphysema

(n = 425)

p value*

Odds ratio (95%)*

Genotype

    

   GG

42 (33%)

83 (20%)

.002

2.02 (1.29-3.15)

   AG+AA

85 (67%)

342 (80%)

  

Allele

    

   G

0.57

0.45

.001

2.61 (1.45-4.76)

   A

0.43

0.55

  
  1. *Multiple logistic regression analysis adjusted for age and sex.
  2. Statistically significant figures (p < 0.05) are shown in boldface.
  3. p values shown above have not been adjusted for multiple testing
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BMC Medical Genetics

ISSN: 1471-2350

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