From: Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases
 | Total (%) N = 1335 | Subjects with emphysema (%) N = 189 | Subjects without emphysema (%) N = 1146 | p values |
---|---|---|---|---|
Men (%) | 717 (53.7%) | 147 (77.8%) | 570 (49.7%) | <0.0001* |
Age (years) | 80.1 ± 9.0 | 81.3 ± 7.3 | 79.9 ± 9.3 | <0.0001†|
History of smoking | Â | Â | Â | Â |
   Smokers | 629 (47.1%) | 146 (77.2%) | 483 (42.1%) | <0.0001‡ |
   Non-smokers | 610 (45.7%) | 32 (16.9%) | 578 (50.4%) |  |
   Data not available | 96 (7.2%) | 11 (5.8%) | 85 (7.4%) |  |
   Pack-years | 21.2 ± 36.3 | 45.0 ± 40.5 | 17.7 ± 31.9 | <0.0001‡ |