Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study

Table 3 The distribution of the predicted EPHX1 phenotypes

Predicted EPHX1 activity	Controls n (%)	Cases n (%)	^§P value	Contingency tables OR (95% CI)	P value
Normal	144 (53.1)	123 (48.4)		1 (reference)
Slow	55 (20.2)	77 (30.3)		1.64 (1.08-2.49)	0.021
Very slow	17 (6.2)	9 (3.5)	0.041	0.62 (0.27-1.44)	0.306
Rapid	55 (20.2)	45 (17.7)		0.96 (0.59-3.19)	0.855

Normal: exon3 Tyr/Tyr and exon 4 His/His or exon 3 Tyr/His and exon 4 His/Arg; Slow: exon 3 Tyr/Tyr and exon 4 His/His; Very slow: exon 3 His/His and exon 4 His/His; Rapid: exon 3 tyr/Tyr and exon 4 Arg/Arg or His/Arg
^§χ²-test was used for the distribution of predicted phenotypes, OR: odds ratio, CI: confidence interval

ISSN: 1471-2350