BMC Medical Genetics

Table 3 Results of cross-sectional association analyses of fasting glucose and BMI.^a

From: The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI

			Full covariate model^b		Simple covariate model^c
Gene	SNP	Risk allele (frequency)	Per risk allele effect size	p	Per risk allele effect size	p
Fasting glucose
KCNJ11	rs5219	T (0.363)	0.001	0.70	-0.001	0.75
PPARG	rs1801282	C (0.883)	0.003	0.56	0.011	0.05
TCF7L2	rs7903146	T (0.303)	0.003	0.44	0.006	0.12
IGF2BP2	rs4402960	T (0.304)	0.007	0.045*	0.011	0.01*
CDKAL1	rs10946398	C (0.303)	0.006	0.08	0.003	0.42
SLC30A8	rs13266634	C (0.699)	0.007	0.05	0.005	0.18
HHEX	rs1111875	G (0.584)	-0.002	0.51	-0.003	0.40
BMI
FTO	rs9939609	A (0.409)	0.009	0.003*	0.013	0.0003*

^a Analyses were conducted on data from the whole study population (n = 4,554) at the 1994/95 survey.
^b Phenotype adjustments, full covariate model:
Fasting glucose: sex, age, age squared, BMI, fasting insulin, SBP, history of diabetes
BMI: sex, age, age squared, fasting insulin, HDL, SBP, DBP
^c Phenotype adjustments for all outcomes, simple covariate model: sex, age
* p < 0.05

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