E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population

Table 2 Clinical characteristics of normotensive and essential hypertensive participants

Index	Total			Male			Female
	NT(n = 495)	EH(n = 490)	P	NT(n = 293)	EH(n = 316)	P	NT(n = 202)	EH(n = 174)	P
Age	51.50 ± 8.92	53.75 ± 7.96	0.85	54.72 ± 5.32	52.1 ± 7.64	0.76	51.50 ± 7.91	52.69 ± 6.88	0.91
BMI (kg/m ² )	22.12 ± 3.12	26.41 ± 3.36	<0.05*	22.1 ± 2.6	24.4 ± 2. 2	0.58	23.9 ± 2.7	27.63 ± 3.05	0.03*
SBP (mmHg)	114.38 ± 11.89	140.29 ± 17.68	<0.01**	106.6 ± 23. 5	142. 4 ± 20. 7	<0.01**	104. 5 ± 24. 1	145.63 ± 19.42	<0.01**
DBP (mmHg)	75.28 ± 9.10	90.44 ± 12.44	<0.01**	80.6 ± 3.7	90.1 ± 10.4	0.01*	72.5 ± 9.6	94.87 ± 11.47	<0.01**
TG(mmol/L)	1.91 ± 0.50	2.03 ± 0.63	0.63	1.07 ± 0. 62	1. 12 ± 0.59	0.72	1.10 ± 0.65	1.32 ± 0.55	0.59
TC(mmol/L)	4.88 ± 1.01	5.38 ± 1.73	<0.05*	4.51 ± 1.22	4.59 ± 1.21	0.93	4.64 ± 1.17	5.36 ± 1.08	<0.05*
HDL-C(mmol/L)	1.62 ± 0.50	1.71 ± 0.61	0.67	0.96 ± 0.73	1.01 ± 0. 32	0.71	1.79 ± 0.31	1.63 ± 0.42	0.64
LDL-C(mmol/L)	1.91 ± 1.79	2.90 ± 1.63	<0.01**	2.08 ± 1.46	2.40 ± 1.48	0.05	2.27 ± 1.41	3.18 ± 1.25	<0.01**
Glu(mmol/L)	4.61 ± 1.45	4.98 ± 1.48	0.78	4.30 ± 1.52	4.40 ± 1.41	0.91	4.60 ± 1.39	4.67 ± 1.74	0.95
BUN(mmol/L)	5.03 ± 1.17	5.89 ± 1.39	0.55	5.08 ± 1.11	6.12 ± 1. 09	0.52	5.02 ± 1.04	5.34 ± 1.22	0.68
Cr(μmol/L)	89.25 ± 15.66	92.05 ± 14.22	0.83	86.23 ± 11.98	90.83 ± 12.12	0.73	87.87 ± 15.57	93.45 ± 12.78	0.54
UA(μmol/L)	86.72 ± 22.46	92.34 ± 17.01	0.69	85.60 ± 20.99	91.48 ± 19.25	0.60	85.79 ± 19.42	90.16 ± 18.77	0.61

All the data were presented as mean ± SD. EH, essential hypertensive patients; NT, normotensive subjects; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; Glu, blood glucose; BUN, blood urea nitrogen; Cr, creatinine; UA, uric acid, * P < 0.05, ** P < 0.01.

ISSN: 1471-2350