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Table 4 Multivariate regression analyses of the SLC2A10 haplotype H4 with PAD in type 2 diabetes.

From: SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10and PAD in type 2 diabetes

Risk factors

Effect estimate

OR (95% CI)

P-values

Age (per year)

0.0812

1.09(1.04,1.13)

3 × 10 -4

Male

-0.0456

0.91(0.38,2.19)

0.83

Hemoglobin A1C (per 1%increase)

0.1046

1.11(0.91,1.36)

0.31

Duration of diabetes (per year)

0.0467

1.05(1,1.1)

0.04

Triglyceride

(per increase of 1mM)

0.2118

1.24(0.79,1.92)

0.34

Total cholesterol

(per increase of 1mM)

-0.1952

0.82(0.54,1.26)

0.36

Systolic blood pressure

(per 1 mmHg increase)

0.0463

1.05(1.03,1.07)

1.9 × 10 -5

Current smoker

-0.2913

0.56(0.22,1.44)

0.22

Body mass index (per kg/m2 increase)

-0.0564

0.95(0.83,1.08)

0.39

H4 haplotype

3.4171

30.47(4.47-208.5)

5 × 10 -4

  1. PAD, peripheral artery disease; OR, odds ratio; CI, confidence interval