Table 3 SLC2A10 haplotype analysis for association with baseline, incident, and all PAD in type 2 diabetes.
Haplotype Sequence | Frequency | Baseline PAD association | Incident PAD association | |||
|---|---|---|---|---|---|---|
P * | OR (95% CI)* | P * | HR (95%CI)* | |||
H1 | A3TAGCCTTTT | 0.051 | 0.87 | 1.28(0.07-22.8) | 0.89 | 1.17(0.13-10.4) |
H2 | G3CTGTGCCCC | 0.499 | 0.01 | 0.20(0.05- 0.75) | 0.80 | 1.20(0.30- 4.72) |
H3 | G2TAGCCTTTT | 0.118 | 0.08 | 4.20(0.82- 21.6) | 0.29 | 0.42(0.09- 2.06) |
H4 | G3TAGCCTTTT | 0.063 | 0.03 | 14.5(1.3-160) | 0.007 | 6.78(1.66- 27.6) |
H5 | G2CAACCTTTT | 0.041 | 0.97 | 1.07(0.04- 29.5) | 0.99 | 1.8 × 10-7 (0-∞) |
H6 | G2CTGTGCCCC | 0.026 | 0.42 | 5.4 × 10-4(0- 40159) | 0.66 | 0.60(0.06-5.99) |
H7 | G3TAGCCTTTC | 0.023 | 0.48 | 1.7 × 10-6 (0-∞) | 0.87 | 1.22(0.10- 14.5) |
H8 | G3CTGTGCCCT | 0.015 | 0.40 | 7.67(0.07- 894) | 0.34 | 3.01(0.31- 29.0) |
Rare haplotypes | 0.15 | 0.26 | 1.36(0.80-2.31) | 0.99 | 4.8 × 10-6 (0-∞) | |