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Table 2 Association analysis of GIP SNPs with Type 2 Diabetes

From: A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population

  rs2291725 rs2291726
Major allele A G
Minor allele G A
Controls   
n 998 1000
Major homozygous 325 297
Hetrozygous 481 472
Minor homozygous 192 231
Major allele frequency 0.57 0.53
Minor allele frequency 0.43 0.47
HWE (P -value) 0.555 0.100
Cases (T2DM)   
n 989 1000
Major homozygous 326 283
Hetrozygous 458 501
Minor homozygous 205 216
Major allele frequency 0.56 0.53
Minor allele frequency 0.44 0.47
HWE (P -value) 0.060 0.837
Tests for association (C.I.: 95% confidence interval)
Odds ratio 1.022 0.998
Allele frequency 0.728 0.974
Dominant model 0.850 0.490
Recessive model 0.406 0.421
  1. n: total number of subjects
  2. HWE - Hardy-Weinberg equilibrium