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Table 3 Genotypic distribution frequencies of codon 392 in exon 7 of estrogen receptor-β gene and major risk factors in study population: breast cancers, versus control groups

From: Estrogen Receptor-Beta Gene Polymorphism in women with Breast Cancer at the Imam Khomeini Hospital Complex, Iran

Characteristic

Group

00a %

01b %

11c %

Test result

Age at menarche(years)

     

</= 12

Case

83.3

15.0

1.7

χ2 = 1.887

P = 0.169

 

control

100

-

-

 
 

total

89.6

9.4

1.0

 

> 12

Case

94.4

4.4

1.1

χ2 = 2.229

P = 0.135

 

control

100

-

-

 
 

total

97.5

2.0

0.5

 

Race

     

Arab & Armani

Case

100

-

-

-

 

control

-

-

-

 
 

total

100

-

-

 

Fars

Case

90.0

10.0

-

χ2 = 9.11

P = 0.003

 

control

100

-

-

 
 

total

95.9

4.1

-

 

Lor & Kurdish

Case

83.3

11.1

5.6

χ2 = 0.697

P = 0.404

 

control

100

-

-

 
 

total

88.9

7.4

3.7

 

Turkish

Case

93.5

4.3

2.2

χ2 = 1.17

P = 0.279

 

control

100

-

-

 
 

total

96.5

2.4

1.1

 

Gilaki & Mazani

Case

87.0

13.0

-

χ2 = 1.527

P = 0.217

 

control

100

-

-

 
 

total

91.2

8.8

-

 

ABO blood Groups

     

A

Case

88.9

11.1

-

χ2 = 4.920

P = 0.027

 

control

100

-

-

 
 

total

95.7

4.3

-

 

B

Case

85.7

14.3

-

χ2 = 5.106

P = 0.024

 

control

100

-

-

 
 

total

95.9

4.1

-

 

AB

Case

100

-

-

-

 

control

100

-

-

 
 

total

100

-

-

 

O

Case

90.3

7.8

1.9

χ2 = 1.884

P = 0.17

 

control

100

-

-

 
 

total

93.6

5.1

1.3

 
  1. a Genotype normal or 329CC, CTC/CTC, b Genotype heterozygote or 329CG, CTC/CTG, Genotype homozygote or 329GG, CTG/CTG