Figure 3

Meiotic recombination in pedigrees with four children. Meiotic recombination sites, on chromosome 5, identified for a family of parents with four children. The top four tracks are normal father-mother-child trios, for each of the four children (d1, s2, s3, d4). The following six tracks are reverse pedigrees for two children with respect to the father. The last six tracks are the reverse pedigrees for the mother's gamete. Vertical lines colored pink, green, blue and orange denote meiotic crossover sites of the child d1, s2, s3 and d4, in that order. The thick black line with arrows denotes a site where two of the four offspring had a meiotic recombination event on their paternal gamete with an additional crossover on the maternal gamete. In this case, the crossover events could have happened on either d1 and s2, or on s3 and d4.