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Table 2 Odds ratios for DRD2 and SLC6A3 genotypes for separate phenotypes of smoking

From: Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population

Smoking phenotype

ORs (95% CI)

 

DRD2genotypes

p-value

SLC6A3genotypes

p-value

 

A1 +

A1 -

 

* 9 +

* 9 -

 

Ever smoking

0.68 (0.42-1.09)

1.47 (0.91-2.38)

0.108

1.00 (0.65-1.57)

0.99 (0.85-1.15)

0.972

Smoking >10 cig./day

0.38 (0.17-0.88)

2.63 (1.14-6.05)

0.0237*

0.39 (0.17-0.89)

2.59 (1.13-5.93)

0.0211*

Regular smoking before the age of 20 years

0.78† (0.37-1.64)

1.29† (0.61-2.69)

0.022*

0.44† (0.22-0.89)

2.27† (1.09-4.50)

0.00175*

   Females

   

0.80 (0.27-2.35)

1.25 (0.43-3.67)

0.677**

   Males

   

0.29 (0.11-0.74)

3.45 (1.36-8.79)

0.007**

  1. † sex-adjusted ORs
  2. * significance level after Bonferroni correction: p = 0.05/2 = 0.025
  3. ** significance level after Bonferroni correction: p = 0.05/3 = 0.017