Table 2 Odds ratios and heterogeneity results for the genetic contrasts of ACE I/D gene polymorphism for restenosis a) after PTCA-balloon, b) after PTCA-STENT, and c) after PTCA and treatment with ACE inhibitors.

11

1.23(1.09–1.38)

1.34(1.09–1.65)

61

< 0.01

7

1.16(1.02–1.31)

1.16(1.02–1.31)

0

0.58

4

1.75(1.29–2.37)

1.85(0.90–3.83)

81

< 0.01

6

1.13(0.99–1.28)

1.13(0.99–1.28)

0

0.46

5

1.99(1.48–2.69)

1.95(1.21–3.14)

59

0.05

11

1.30(1.09–1.54)

1.42(1.07–1.91)

52

0.02

7

1.20(1.00–1.45)

1.20(1.00–1.45)

0

0.57

4

2.29(1.38–3.80)

1.88(0.65–5.45)

70

0.02

6

1.17(0.96–1.41)

1.19(0.96–1.47)

14

0.32

5

2.24(1.45–3.46)

2.15(1.12–4.10)

50

0.09

11

1.32(1.08–1.61)

1.36(1.05–1.76)

27

0.19

7

1.23(0.98–1.54)

1.23(0.96–1.57)

10

0.35

4

1.78(1.12–2.82)

1.87(0.98–3.58)

44

0.15

6

1.18(0.95–1.48)

1.18(0.92–1.51)

16

0.31

5

2.27(1.38–3.72)

2.21(1.33–3.66)

0

0.62

11

1.30(1.09–1.54)

1.42(1.07–1.91)

52

0.02

7

1.20(1.00–1.45)

1.20(1.00–1.45)

0

0.57

4

2.29(1.38–3.80)

1.88(0.65–5.45)

70

0.02

6

1.17(0.96–1.41)

1.19(0.96–1.47)

14

0.32

5

2.24(1.45–3.46)

2.15(1.12–4.10)

50

0.09

11

0.96(0.82–1.13)

0.95(0.79–1.15)

14

0.01

7

0.97(0.81–1.15)

0.95(0.77–1.18)

21

0.27

4

0.94(0.61–1.45)

0.93(0.55–1.55)

26

0.26

6

0.98(0.82–1.17)

0.97(0.78–1.21)

29

0.22

5

0.87(0.57–1.32)

0.87(0.56–1.36)

7

0.37

Population

Studies

Fixed effects

OR(95%ci)

Random effects

OR(95%ci)

I²

(%)

p-value

Q-test

11

1.03(0.94–1.12)

1.04(0.92–1.16)

25

0.21

7

1.01(0.92–1.11)

1.01(0.92–1.11)

0

0.45

2

0.87(0.61–1.26)

0.88(0.61–1.26)

na

0.61

6

1.02(0.93–1.12)

1.02(0.93–1.12)

1

0.41

5

1.05(0.84–1.31)

1.07(0.77–1.49)

52

0.08

11

1.05(0.92–1.21)

1.07(0.92–1.24)

7

0.38

7

1.03(0.89–1.20)

1.05(0.88–1.26)

20

0.28

2

1.18(0.61–2.27)

1.18(0.61–2.28)

na

0.68

6

1.04(0.89–1.21)

1.07(0.87–1.32)

32

0.20

5

1.16(0.82–1.65)

1.17(0.82–1.66)

0

0.56

12

1.01(0.87–1.16)

0.96(0.79–1.18)

30

0.16

7

1.00(0.86–1.17)

1.00(0.86–1.16)

0

0.45

3

0.67(0.42–1.06)

0.67(0.42–1.07)

0

0.88

6

1.02(0.88–1.19)

1.02(0.87–1.19)

0

0.43

6

0.93(0.67–1.30)

0.99(0.58–1.68)

51

0.07

Population

Studies

Fixed effects

OR(95%ci)

Random effects

OR(95%ci)

I²

(%)

p-value

Q-test

3

1.10(0.81–1.48)

1.10(0.81–1.48)

0

0.42

3

1.50(0.97–2.28)

1.74(0.78–3.87)

42.8

0.17

5

0.85(0.52–1.38)

0.86(0.43–1.74)

31.2

0.21

3

0.71(0.41–1.22)

0.70(0.41–1.22)

0

0.93

2

1.64(0.57–4.74)

1.22(0.09–16.61)

na

0.05