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Table 3 Haplotype frequency of three PRNP polymorphisms in the normal population, AD patients, and VaD patients

From: Lack of association between PRNP 1368 polymorphism and Alzheimer's disease or vascular dementia

Haplotypes

1368

Codon 129

Codon 219

Frequency

P value

    

AD

VaD

Control

AD vs Control

VaD vs Control

AD vs VaD

ht1

C

A

G

0.5592

0.5622

0.5951

-

-

-

ht2

T

A

G

0.3618

0.3623

0.3450

0.479

0.451

0.996

ht3

T

A

A

0.0263

0.0142

0.0292

0.990

0.167

0.215

ht4

T

G

G

0.0197

0.0037

0.0115

0.280

0.252

0.050

ht5

C

A

A

0.0164

0.0352

0.0109

0.333

0.013

0.226

ht6

C

G

G

0.0066

0.0224

0.0083

1.0

0.078

0.197

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BMC Medical Genetics

ISSN: 1471-2350

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