Table 2 Genotype and allele frequencies of the PRNP 1368 polymorphism in the normal population, AD patients, and VaD patients
From: Lack of association between PRNP 1368 polymorphism and Alzheimer's disease or vascular dementia
| Â | Control (n = 268) | AD (n = 152) | VaD (n = 192) | AD vs Control | VaD vs control | ||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | ORa | 95% CIb | P value | OR | 95% CI | P value |
Genotype frequency | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   CC | 103 (38.4) | 56 (36.8) | 84 (43.8) | - | - | - | - | - | - |
   CT | 124 (46.3) | 67 (44.1) | 74 (38.5) | 0.994 | 0.640 – 1.544 | 0.978 | 0.732 | 0.487 – 1.100 | 0.133 |
   TT | 41 (15.3) | 29 (20.1) | 34 (17.7) | 1.301 | 0.731 – 2.315 | 0.371 | 1.017 | 0.594 – 1.742 | 0.952 |
Allele frequency | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   C | 330 (61.6) | 179 (58.9) | 242 (63.0) | - | - | - | - | - | - |
   T | 206 (38.4) | 125 (41.1) | 142 (37.0) | 1.119 | 0.839 – 1.491 | 0.444 | 0.940 | 0.717 – 1.232 | 0.654 |