Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles – a cohort study

BMC Medical Genetics

Table 1 Analysis of association between LXR alleles and T2D in French cases vs control

a) Common allele is written first. b) #11 = number of subjects homozygous for common allele, #12 = number of heterozygous subjects, #22 = number of subjects homozygous for rare allele. c) Major allele frequency. d) HWE P values were calculated in HAPLOVIEW [32]. e) O.R. ± C.I. = odds ratio ± confidence intervals. ORs were calculated as (number allele 2 among cases * number allele 1 among controls)/(number allele 1 among cases * number allele 2 among controls). f) Pearson's Chi² (d.f. = 1) was used to compare allele frequencies between T2D-cases and controls. g) ND = non-diabetic controls, T2D = type 2 diabete

ISSN: 1471-2350