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Table 6 Association of IL6 haplotypes with COPD and ln(CRP)

From: IL6 and CRPhaplotypes are associated with COPD risk and systemic inflammation: a case-control study

  COPD * Ln (CRP) †
Haplotype OR (95%CI) P-value Coefficient ± SE P-value
H1 0.92 (0.56–1.51) 0.75 0.005 ± 0.17 0.98
H2 4.82 (1.64–4.18) 0.004 -0.94 ± 0.27 0.0005
H3 1.71 (0.85–3.44) 0.13 -0.12 ± 0.21 0.54
H4 REFERENT REFERENT
H5 1.01 (0.64–1.60) 0.95 0.01 ± 0.17 0.93
H6 0.93 (0.51–1.67) 0.80 -0.36 ± 0.22 0.10
H7 0.71 (0.37–1.36) 0.3 -0.02 ± 0.24 0.94
Others‡ 1.48 (0.79–2.78) 0.22 -0.07 ± 0.20 0.73
  1. * Logistic regression analyses were adjusted for age, sex and tobacco consumption (pack-years smoked).
  2. † Linear regression analyses were adjusted for age, sex, BMI and 6MWD.
  3. ‡ Rare haplotypes (frequency < 2.5%) were coded in aggregate as "others"