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Table 1 Quantitative obesity-related measures in the combined study sample

From: Studies of CTNNBL1 and FDFT1variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes

   n
(men/woman)
Age
(years)
BMI
(kg/m2)
Body weight
(kg)
Waist circumference
(cm)
Height
(cm)
CTNNBL1 rs6013029 GG 13,579 (7,113/6,466) 54 ± 10 27.5 ± 4.8 81.0 ± 16.2 92.5 ± 14.3 171.2 ± 9.2
  GT 1,318 (702/616) 55 ± 10 27.7 ± 4.9 82.0 ± 16.5 93.1 ± 14.5 171.8 ± 9.1
  TT 22 (9/13) 56 ± 9 27.6 ± 4.5 80.2 ± 12.5 91.9 ± 11.9 170.8 ± 7.3
  Per allele
effect size
(95% CI)
   0.16
(-0.10–0.42)
0.89
(0.08–1.69)
0.43
(-0.26–1.12)
0.48
(0.13–0.82)
  P add    0.2 0.03 0.2 0.007
  P dom    0.2 0.03 0.2 0.009
CTNNBL1 rs6020846 AA 13,317 (6,972/6,345) 54 ± 10 27.5 ± 4.8 80.9 ± 16.2 92.5 ± 14.3 171.2 ± 9.2
  AG 1,527 (821/706) 55 ± 10 27.7 ± 4.9 82.1 ± 16.5 93.2 ± 14.3 171.9 ± 9.1
  GG 42 (23/19) 57 ± 9 27.8 ± 4.5 83.7 ± 15.4 94.5 ± 14.0 173.2 ± 8.4
  Per allele
effect size
(95% CI)
   0.17
(-0.07–0.41)
1.02
(0.28–1.76)
0.54
(-0.09–1.17)
0.56
(0.25–0.88)
  P add    0.2 0.007 0.1 5 × 10-4
  P dom    0.2 0.008 0.1 0.001
FDFT1
rs7001819
TT 5,929
(3,062/2,867)
55 ± 10 27.5 ± 4.9 80.8 ± 16.3 92.4 ± 14.4 171.1 ± 9.2
  TC 6,823 (3,597/3,226) 54 ± 10 28.0 ± 4.9 81.3 ± 16.4 92.4 ± 14.4 171.5 ± 9.3
  CC 1,886 (1,021/865) 55 ± 10 27.5 ± 4.8 81.0 ± 15.8 92.6 ± 13.9 171.3 ± 9.1
  Per allele
effect size
(95% CI)
   0.01
(-0.10–0.13)
0.06
(-0.29–0.41)
0.03
(-0.28–0.33)
0.06
(-0.09–0.21)
  P add    0.8 0.8 0.9 0.4
  P dom    0.6 0.3 0.5 0.07
  1. Data are means ± standard deviation. p-values were calculated assuming a additive (p add) and a dominant (p dom) model for all variants. Known type 2 diabetic patients were excluded from the analyses. Per allele effect sizes was calculated using linear models assuming an additive model. Adjustments were made for the effect of age and sex.