Figure 3

SNP comparison of rs9475431, rs9475430, and rs9475429 on BMP5 promoter activity. Luciferase reporter assays comparing the mean transcriptional activities of haplotypes containing the T allele of rs9475431 and haplotypes containing the G allele, haplotypes containing the T allele of rs9475430 and haplotypes containing the C allele, and haplotypes containing the T allele of rs9475429 and haplotypes containing the A allele were performed in MG63 cells. Data shown are the mean ± SD. * P = 2.4 × 10^-3. NS is not significant.