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Table 7 Proportions of cases and controls with different SNP-genotypes at the CSF2 locus and risk estimates from conditional logistic regression (CLR) analysis of 651 matched case-control pairs for each SNP for scarring trachoma.

From: Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians

    Multiplicative model Dominant model Recessive model
Genotype # of genotypes (freq) CLR OR (95%CI) OR (95%CI)
  TS cases controls OR (95%CI) P value P value P value
GM-CSF2_27348 TT 391(0.65) 384(0.61) Reference - 0.86(0.67,1.09) 0.60(0.33,0.084)
GM-CSF2_27348 TA 193(0.32) 207(0.33) 0.90(0.70,1.57) 0.414 0.200 0.084
GM-CSF2_27348 AA 22 (0.04) 36 (0.06) 0.58(0.32,1.04) 0.069   
Test for trend    0.84(0.69,1.03) 0.091   
GM-CSF2_2069614 CC 206(0.32) 198(0.31) Reference - 0.88(0.68,1.28) 0.99 (0.74,1.31)
GM-CSF2_2069614 CT 306(0.48) 316(0.49) 0.87(0.67,1.31) 0.300 0.310 0.922
GM-CSF2_2069614 TT 124(0.19) 130(0.20) 0.90(0.65,1.26) 0.546   
Test for trend    0.94(0.80,1.11) 0.467   
GM-CSF2_27438 AA 215(0.33) 233(0.36) Reference - 1.08(0.85,1.37) 1.37 (1.02,1.85)
GM-CSF2_27438 AG 301(0.47) 318(0.49) 1.00(0.78,1.29) 0.991 0.542 0.037
GM-CSF2_27438 GG 126(0.20) 100(0.15) 1.37(0.98,1.93) 0.066   
Test for trend    1.14(0.97,1.35) 0.113