Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs

BMC Medical Genetics

Table 1 Sample information

Sample	PED	IND	AIND	ASP	ACP	APOE ε4+	APOE ε4-	AAO ± SD
SWE	52	168	130	102	14	87	10	69.1 ± 6.2
UK	70	148	148	87	0	51	16	75.0 ± 5.9
USA	139	369	302	191*	3	143	16	72.6 ± 6.1
Total	261	685	580	380	17	281	42	72.4 ± 5.5

PED: number of pedigrees, IND: number of genotyped individuals, AIND: number of genotyped affected individuals, ASP: number of genotyped affected sib-pairs, ACP: number of genotyped pairs of affected first cousins, APOE ε4+: number of ARPs where both individuals have at least one APOE ε4 allele, APOE ε4-: number of ARPs where neither individual has an APOE ε4 allele, AAO: age at onset, SD: standard deviation. * Including one half-sib pair.

ISSN: 1471-2350