Table 4 Analysis of age stratified association of rs3754734 and rs2011616 with hypertension in stage 2.
SNP | Age group (years) | Genotype | Allele (Major/Minor) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Case | Control | OR*(95%CI) | P | case | control | OR (95%CI) | P |
rs3754734 | Â | TT/TG/GG | TT vs. TG/GG | Â | T/G | T/G | Â | Â | |
| Â | < 50 | 217/193/58 | 188/220/59 | 0.768(0.584-1.009) | 0.058 | 0.670/0.330 | 0.638/0.362 | 0.87(0.72-1.06) | 0.174 |
| Â | 50-60 | 161/183/48 | 172/191/55 | 0.985(0.735-1.320) | 0.919 | 0.644/0.356 | 0.640/0.360 | 1.02(0.83-1.25) | 0.876 |
| Â | > 60 | 175/222/58 | 173/159/49 | 1.346(1.003-1.806) | 0.048 | 0.629/0.371 | 0.663/0.337 | 0.86(0.70-1.05) | 0.151 |
rs2011616 | Â | GG/GA/AA | GG vs. GA/AA | Â | G/A | G/A | Â | Â | |
| Â | < 50 | 245/177/41 | 212/213/38 | 0.745(0.568-0.977) | 0.033 | 0.720/0.280 | 0.688/0.312 | 1.17(0.96-1.43) | 0.126 |
| Â | 50-60 | 182/170/40 | 195/187/33 | 1.013(0.758-1.353) | 0.932 | 0.681/0.319 | 0.695/0.305 | 0.94(0.76-1.16) | 0.543 |
| Â | > 60 | 216/208/28 | 201/141/39 | 1.437(1.072-1.926) | 0.015 | 0.708/0.292 | 0.713/0.287 | 0.98(0.79-1.21) | 0.835 |