Table 2 Distribution of genotypic frequencies for GSTM1 and GSTT1 in the study population
Genotypes | Total n (%) 514 (100%) | Cases n (%) 245 (100%) | Controls n (%) 269 (100%) | OR | CI 95% | p value |
|---|---|---|---|---|---|---|
# GSTM1-active (+) | 368 (71.60) | 183 (74.69) | 185 (68.77) | 1.00 (reference group) | ||
GSTM1-null (−) | 146 (28.40) | 62 (25.30) | 84 (31.23) | 0.74 | 0.50–1.09 | 0.14 |
# GSTT1-active (+) | 194 (37.74) | 75 (30.61) | 119 (44.24) | 1.00 (reference group) | ||
GSTT1-null (−) | 320 (62.26) | 170 (69.39) | 150 (55.76) | 1.79 | 1.25–2.58 | 0.001* |
# GSTM1(+) / GSTT1(+) | 125 (24.32) | 45 (18.37) | 80 (29.74) | 1.00 (reference group) | ||
GSTM1(−) / GSTT1(+) | 69 (13.42) | 30 (12.25) | 39 (14.50) | 1.36 | 0.75–2.49 | 0.35 |
GSTM1(+) / GSTT1(−) | 243 (47.28) | 138 (56.32) | 105 (39.03) | 2.33 | 1.50–3.65 | < 0.001* |
GSTM1(−) / GSTT1(−) | 77 (14.98) | 32 (13.06) | 45 (16.73) | 1.26 | 0.71–2.26 | 0.45 |