Table 2 Characteristics of the studies included in the meta-analysis of the association between SNPs and cardiocerebrovascular diseases
SNP loci | Year | First author | Ethnicity | Cancer/disease | Controla | Sample size (case-control) | Case | Control | OR(95%CI) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hom†wild | Het†| Hom variant | Hom†wild | Het†| Hom variant | ||||||||
rs505922 | 2017 | H. Li | Asian | Ischemic stroke | PB | 991/1002 | 511 | 406 | 74 | 657 | 306 | 39 | 1.64(1.41–1.90) |
2017 | H. Zhang | Asian | Large artery atherosclerotic stroke | PB | 644/642 | 146 | 325 | 173 | 129 | 322 | 191 | 0.90(0.77–1.05) | |
2016 | W. Hernandez | African | Venous Thrombosis | HB | 146 /432 | – | – | – | – | – | – | 1.52(1.20–2.00) | |
2013 | FM.Williams-a‡ | Caucasian | Ischemic stroke | HB | 4092/8383 | – | – | – | – | – | – | 1.06(1.01–1.14) | |
2013 | FM.Williams-b‡ | Caucasian | Ischemic stroke | HB | 8443 /54810 | – | – | – | – | – | – | 1.07(1.03–1.11) | |
2011 | MP. Reilly | Caucasian | Myocardial infarction | HB | 5783/3644 | – | – | – | – | – | – | 1.20(1.13–1.28) | |
2009 | DA.Trégouet-a§ | Caucasian | Venous thromboembolism | PB | 419/1228 | 97 | 209 | 113 | 519 | 559 | 150 | 2.01(1.71–2.35) | |
2009 | DA.Trégouet-b§ | Caucasian | Venous thromboembolism | PB | 1150/801 | 299 | 575 | 276 | 339 | 364 | 98 | 1.79(1.57–2.04) | |
2009 | DA.Trégouet-c§ | Caucasian | Venous thromboembolism | PB | 607/607 | 177 | 302 | 128 | 265 | 272 | 70 | 1.66(1.41–1.95) | |
rs657152 | 2016 | W. Hernandez | African | Venous Thrombosis | HB | 146 /432 | – | – | – | – | – | – | 1.39(1.10–1.80) |
2011 | MP. Reilly | Caucasian | Myocardial infarction | HB | 5783/3644 | – | – | – | – | – | – | 1.19(1.12–1.27) | |
2009 | DA.Trégouet-a§ | Caucasian | Venous thromboembolism | PB | 419/1228 | 89 | 208 | 122 | 472 | 579 | 177 | 1.91(1.63–2.24) | |
2009 | DA.Trégouet-b§ | Caucasian | Venous thromboembolism | PB | 1150/801 | 276 | 575 | 299 | 318 | 373 | 110 | 1.77(1.55–2.02) | |
2009 | DA.Trégouet-c§ | Caucasian | Venous thromboembolism | PB | 607/607 | 171 | 302 | 134 | 249 | 280 | 78 | 1.58(1.34–1.86) | |